Urban planners and ecologists have long debated the relationship between the structure of urban landscapes and social activities. There have, however, been very few discussions as to whether any such relationships might depend on the scales of observation. This work applies a hierarchical zoning technique to data from the city of Quito, Ecuador, to examine how relationships between typical spatial landscape metrics and social indicators depend on zoning scales. Our results showed that the estimates of both landscape heterogeneity features and social indicators significantly depend on the zoning scale. The mean values of the typical landscape metrics and the social indicators all exhibited predictable responses to a changing zoning scale, suggesting a consistent and significant scaling relationship within the multiple zoning scales.