The comes and goes of lipid membranes under the lens of computer simulations

When phospholipids dissolve in water they self-assemble into a variety of structures of which bilayers have the greatest biological relevance. Bio-membranes are the most complex examples of lipid bilayers as they have evolved to accommodate the needs of specialized cells, organelles, and other sub-c...

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Autor principal: Del Pópolo, M.
Formato: documento de conferencia
Lenguaje:Español
Publicado: 2019
Materias:
Acceso en línea:http://bdigital.uncu.edu.ar/12587
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author Del Pópolo, M.
author_facet Del Pópolo, M.
author_sort Del Pópolo, M.
collection Repositorio
description When phospholipids dissolve in water they self-assemble into a variety of structures of which bilayers have the greatest biological relevance. Bio-membranes are the most complex examples of lipid bilayers as they have evolved to accommodate the needs of specialized cells, organelles, and other sub-cellular structures. However, even the simplest lipid bilayer offers a repertoire of behaviours that is amenable of exploration with different levels of resolution in space and time. For example, while certain properties of the membranes are well described considering the membrane as an elastic sheet, others demand a more detailed description that takes into account the atomic nature of the lipids and the forces that keep the bilayer together. Between these two extreme representations of the membrane, one fairly schematic the other very elaborate, there is a range of “coarse-grain" models that can be interrogated with the aid of computer simulations.
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spelling uncu-125872019-08-13T13:14:53Z The comes and goes of lipid membranes under the lens of computer simulations Del Pópolo, M. Metabolismo de los lípidos Membrana Celular When phospholipids dissolve in water they self-assemble into a variety of structures of which bilayers have the greatest biological relevance. Bio-membranes are the most complex examples of lipid bilayers as they have evolved to accommodate the needs of specialized cells, organelles, and other sub-cellular structures. However, even the simplest lipid bilayer offers a repertoire of behaviours that is amenable of exploration with different levels of resolution in space and time. For example, while certain properties of the membranes are well described considering the membrane as an elastic sheet, others demand a more detailed description that takes into account the atomic nature of the lipids and the forces that keep the bilayer together. Between these two extreme representations of the membrane, one fairly schematic the other very elaborate, there is a range of “coarse-grain" models that can be interrogated with the aid of computer simulations. Fil: Del Pópolo, M.. Consejo Nacional de Investigaciones Científicas y Técnicas. FCM, UNCuyo 2019-08-14 spa Español info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar/ documento de conferencia info:eu-repo/semantics/conferenceObject info:ar-repo/semantics/documento de conferencia info:eu-repo/semantics/acceptedVersion application/pdf http://bdigital.uncu.edu.ar/12587
spellingShingle Metabolismo de los lípidos
Membrana Celular
Del Pópolo, M.
The comes and goes of lipid membranes under the lens of computer simulations
title The comes and goes of lipid membranes under the lens of computer simulations
title_full The comes and goes of lipid membranes under the lens of computer simulations
title_fullStr The comes and goes of lipid membranes under the lens of computer simulations
title_full_unstemmed The comes and goes of lipid membranes under the lens of computer simulations
title_short The comes and goes of lipid membranes under the lens of computer simulations
title_sort comes and goes of lipid membranes under the lens of computer simulations
topic Metabolismo de los lípidos
Membrana Celular
url http://bdigital.uncu.edu.ar/12587