The comes and goes of lipid membranes under the lens of computer simulations
When phospholipids dissolve in water they self-assemble into a variety of structures of which bilayers have the greatest biological relevance. Bio-membranes are the most complex examples of lipid bilayers as they have evolved to accommodate the needs of specialized cells, organelles, and other sub-c...
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Formato: | documento de conferencia |
Lenguaje: | Español |
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2019
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Acceso en línea: | http://bdigital.uncu.edu.ar/12587 |
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author | Del Pópolo, M. |
author_facet | Del Pópolo, M. |
author_sort | Del Pópolo, M. |
collection | Repositorio |
description | When phospholipids dissolve in water they self-assemble into a variety of structures of which
bilayers have the greatest biological relevance. Bio-membranes are the most complex examples of
lipid bilayers as they have evolved to accommodate the needs of specialized cells, organelles, and
other sub-cellular structures. However, even the simplest lipid bilayer offers a repertoire of
behaviours that is amenable of exploration with different levels of resolution in space and time. For
example, while certain properties of the membranes are well described considering the membrane
as an elastic sheet, others demand a more detailed description that takes into account the atomic
nature of the lipids and the forces that keep the bilayer together. Between these two extreme
representations of the membrane, one fairly schematic the other very elaborate, there is a range of
“coarse-grain" models that can be interrogated with the aid of computer simulations.
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format | documento de conferencia |
id | uncu-12587 |
institution | Biblioteca Digital - UNCUYO |
language | Español |
publishDate | 2019 |
record_format | ojs |
spelling | uncu-125872019-08-13T13:14:53Z The comes and goes of lipid membranes under the lens of computer simulations Del Pópolo, M. Metabolismo de los lípidos Membrana Celular When phospholipids dissolve in water they self-assemble into a variety of structures of which bilayers have the greatest biological relevance. Bio-membranes are the most complex examples of lipid bilayers as they have evolved to accommodate the needs of specialized cells, organelles, and other sub-cellular structures. However, even the simplest lipid bilayer offers a repertoire of behaviours that is amenable of exploration with different levels of resolution in space and time. For example, while certain properties of the membranes are well described considering the membrane as an elastic sheet, others demand a more detailed description that takes into account the atomic nature of the lipids and the forces that keep the bilayer together. Between these two extreme representations of the membrane, one fairly schematic the other very elaborate, there is a range of “coarse-grain" models that can be interrogated with the aid of computer simulations. Fil: Del Pópolo, M.. Consejo Nacional de Investigaciones Científicas y Técnicas. FCM, UNCuyo 2019-08-14 spa Español info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar/ documento de conferencia info:eu-repo/semantics/conferenceObject info:ar-repo/semantics/documento de conferencia info:eu-repo/semantics/acceptedVersion application/pdf http://bdigital.uncu.edu.ar/12587 |
spellingShingle | Metabolismo de los lípidos Membrana Celular Del Pópolo, M. The comes and goes of lipid membranes under the lens of computer simulations |
title | The comes and goes of lipid membranes under the lens of computer simulations
|
title_full | The comes and goes of lipid membranes under the lens of computer simulations
|
title_fullStr | The comes and goes of lipid membranes under the lens of computer simulations
|
title_full_unstemmed | The comes and goes of lipid membranes under the lens of computer simulations
|
title_short | The comes and goes of lipid membranes under the lens of computer simulations
|
title_sort | comes and goes of lipid membranes under the lens of computer simulations |
topic | Metabolismo de los lípidos Membrana Celular |
url | http://bdigital.uncu.edu.ar/12587 |