| Sumario: | Nowadays, Knowledge Intensive Organizations (OIC in Spanish) and the contribution they make to innovation processes must be taken into account for the development of a country. In the case of Colombia, Research Centers of Excellence (CIE in Spanish) have been recognized by the National Science, Technology and Innovation System for several years due to their contributions to the generation of cutting-edge knowledge in different areas. In this context, this article aims to propose a characterization of human management macro-processes for OICs reached from a qualitative research, case-study of the CIE, and specifically from the analysis of their human management processes. It is important to recognize the differences between traditional organizations and OICs which has implied a re-evaluation of the worker and its role within the organization, reason why human management within ICOs cannot be the same. This is one of the conclusions derived from the study of the CIE and from the comparison of the results with previous literature, which defines the contribution of this article.
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